All of the following statements regarding biovailability of a drug are true except______________?

A.\tIt is the proportion (fraction) of unchanged drug that reaches the systemic circulation
B.\tBiovailability of an orally administered drug can be calculated by comparing the area under cure (o-a) after oral and intravenous (IV) administration
C.\tLow oral biovailability always and necessarily mean poor absorptionCorrect Answer
D.\tBiovailability can be determined from plasma concentration or urinary excretion data
Correct Option: C.\tLow oral biovailability always and necessarily mean poor absorption

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